Search results for "Clinical state"

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Schizophrenic patients who smoke have a faster finger tapping rate than non-smokers

2002

The increased rate of smoking in schizophrenia patients remains unexplained and may reflect attempts at self-treatment. The effect sought from smoking may be related to nicotine's stimulating action. We tested this hypothesis by examining the relationship between smoking status and finger tapping rate, a measure of central processing, in schizophrenia patients treated with atypical antipsychotics. Smokers showed significantly faster finger tapping rates than non-smokers. This was not related to clinical state, illness chronicity, medication side-effects, antipsychotic dose or plasma concentrations. Nicotine can improve central processing in medicated schizophrenia patients and this may cons…

AdultMaleNicotinemedicine.medical_specialtyPatientsMovementmedicine.medical_treatmentClinical stateFingersNicotineInternal medicinemedicineHumansPharmacology (medical)Nicotinic AgonistsAntipsychoticPsychiatryBiological PsychiatryPharmacologySmokeAnalysis of VarianceSmokingMiddle Agedmedicine.diseasePsychiatry and Mental healthNeurologySchizophreniaFinger tappingPlasma concentrationSchizophreniaSmoking statusNeurology (clinical)PsychologyPsychomotor Performancemedicine.drugEuropean Neuropsychopharmacology
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Clinical states of cirrhosis and competing risks.

2018

The clinical course of cirrhosis is mostly determined by the progressive increase of portal hypertension, hyperdynamic circulation, bacterial translocation and activation of systemic inflammation. Different disease states, encompassing compensated and decompensated cirrhosis and a late decompensated state, are related to the progression of these mechanisms and may be recognised by haemodynamic or clinical characteristics. While these disease states do not follow a predictable sequence, they correspond to varying mortality risk. Acute-on-chronic liver failure may occur either in decompensated or in compensated cirrhosis and is always associated with a high short-term mortality. The increasin…

Liver Cirrhosismedicine.medical_specialtyCirrhosisClinical course of cirrhosiDiseaseCompeting risksSystemic inflammationRisk AssessmentMultistate models for cirrhosi03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansPortal hypertensionIntensive care medicineCirrhosiHepatologybusiness.industryClinical courseClinical states of cirrhosiCompeting riskHepatologymedicine.diseasePrognosisCumulative incidence function030220 oncology & carcinogenesisHyperdynamic circulationDisease ProgressionPortal hypertension030211 gastroenterology & hepatologymedicine.symptombusinessJournal of hepatology
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